Okwangoku, i-neotame yamkelwe kumazwe angaphezu kwe-100 ukuba isetyenziswe kwiintlobo ezingaphezu kwe-1000 zeemveliso.
Ilungele ukusetyenziswa kwiziselo ezithambileyo ezinekhabhoni, iyogathi, iikeyiki, umgubo wesiselo, iintsini zeqamza phakathi kokunye ukutya.Ingasetyenziswa njengetafile ephezulu yesweetener kwiziselo ezishushu njengekofu.Igubungela incasa ekrakra .
I-HuaSweet neotame ihambelana nomgangatho wesizwe waseTshayina we-GB29944 kwaye idibana ngokungqongqo ne-FCCVIII, i-USP, i-JECFA kunye neenkcukacha ze-EP.I-HuaSweet iseke inethiwekhi yokuthengisa kumazwe angaphezu kwamashumi asibhozo kuwo wonke uMzantsi-mpuma Asia, iYurophu, uMzantsi Merika, uMntla Merika kunye neAfrika.
Ngo-2002, i-FDA yamvuma njenge-sweetener engenazo izondlo kunye nesiphuculi sencasa ngaphakathi e-United States ekutyeni ngokubanzi, ngaphandle kwenyama kunye nenkukhu. [3]Ngo-2010, yamkelwa ukuba isetyenziswe ekutyeni ngaphakathi kwe-EU kunye nenombolo E961 [5].Ikwavunyiwe njengesongezo kwamanye amazwe amaninzi angaphandle kwe-US kunye ne-EU.
E-US kunye ne-EU, ukuthathwa kwemihla ngemihla eyamkelekileyo (ADI) ye-neotame kubantu yi-0.3 kunye ne-2 mg ngekhilogram ye-bodyweight (mg / kg bw), ngokulandelanayo.I-NOAEL yabantu yi-200 mg / kg bw ngosuku ngaphakathi kwe-EU.
Uqikelelo olunokwenzeka lwemihla ngemihla ekutyeni lungaphantsi kwamanqanaba e-ADI.I-neotame etyiweyo inokwenza i-phenylalanine, kodwa ekusebenziseni okuqhelekileyo kwe-neotame, oku akubalulekanga kwabo bane-phenylketonuria.Kananjalo ayinayo imiphumo emibi kuhlobo lwe-2 yeswekile.Ayithathwa njenge-carcinogenic okanye i-mutagenic.
Iziko leNzululwazi kuMdla woLuntu libeka i-neotame njengekhuselekile.